Arthrogryposis Multiplex Congenita, Epileptic Seizures and Cortical Dysplasia: a Case Report

We have presented a case of a 22-year-old patient having a rare variety of arthrogryposis multiplex congenita arthrogryposis with epileptic seizures and defect in neural migration. We have described the patient’s disease history, the clinical, and laboratory data by giving prominence to the lack of mental retardation and the late onset of the generalized tonic-clonic seizures, despite the present cortical dysplasia. We have also discussed cases reported by other investigators. We consider that our case report is a contribution to the knowledge about the clinical manifestations, the possible results from neuroimaging and electrophysiological methods, and the progression of arthrogryposis multiplex congenita.